Senior Technical Project Manager

Tempus

Posted on: May 6, 2026

Closing: June 05, 2026

Salary: 135,000.00 - 165,000.00 per year

Position Type: Full Time

Job Description

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are seeking a highly motivated Senior Technical Project Manager with a strong background in healthcare technology, EHR integrations, and data interoperability. This individual will be responsible for driving the successful execution of clinical data integration projects, collaborating across teams to ensure smooth onboarding, timely delivery, and efficient communication between Tempus and healthcare partners. The ideal candidate will have a deep understanding of EHR workflows, HL7/FHIR integrations, and project management best practices to enable streamlined implementation.

Responsibilities:
  • Lead and manage multiple EHR integration and data ingestion projects, ensuring timelines, deliverables, and stakeholder expectations are met.
  • Serve as the primary liaison between external healthcare organizations, internal engineering teams, and clinical stakeholders, facilitating clear communication and project alignment.
  • Define project scope, timelines, risks, and dependencies while developing detailed implementation plans and workflows.
  • Coordinate with technical teams on HL7 v2, FHIR API, and data transformation requirements to support interoperability.
  • Work closely with clinical informatics, engineering, and support teams to ensure data quality, compliance, and usability.
  • Manage customer expectations, ensuring a seamless experience during implementation, testing, and go-live support.
  • Identify process improvement opportunities to enhance efficiency, scalability, and automation in the integration workflow.
  • Maintain and refine project documentation, best practices, and training materials to support ongoing optimization efforts.

Required Skills and Qualifications:
  • Strong understanding of healthcare interoperability standards (HL7 v2, FHIR, CDA, X12) and data exchange processes.
  • Familiarity with API-based integrations (REST, OAuth 2.0) and data transformation workflows.
  • Ability to manage multiple projects simultaneously, balancing priorities and resource constraints.
  • Strong problem-solving skills and ability to anticipate project risks, dependencies, and mitigation strategies.

Preferred Qualifications:
  • Salesforce reporting
  • Familiarity with formats: JSON, XML
  • Understanding with document repositories: OnBase, Epic Blob
  • Understanding with integration engines: Iguana, Ellkay, CorePoint, Cloverleaf, etc
  • Familiarity with EMRs: Epic, Flatiron, McKesson iKnowMed, Meditech, etc.
  • Understanding of database platforms (On-Prem & Cloud-based): SQL Server, MySQL, AWS Redshift, Google PostgreSQL, Oracle
  • Experience with healthcare terminology concept codes (SNOMED, ICD-10, LOINC, etc.)
  • Knowledge of oncology or genomic data

$135,000-$165,000

The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Tempus

Posted on: May 6, 2026

Closing: June 05, 2026

Salary: 135,000.00 - 165,000.00 per year

Position Type: Full Time

Career Focus: Project Management

This role is part of a curated selection of life science opportunities featured on Xtalks. Employers may request edits or removal here.

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